Berdyshev E V, Vaskovsky V E, Vaschenko M A
Institute of Marine Biology, Vladivostok, Russia.
Comp Biochem Physiol B Biochem Mol Biol. 1995 Mar;110(3):629-32. doi: 10.1016/0305-0491(94)00161-m.
This study reports on the effect of PAF on sperm motility, fertilization and early embryo development in the sea urchin Strongylocentrotus intermedius. PAF proved to be the amplifier of sperm motility and fertilizing capability at 10(-8)-10(-9) M and was toxic at higher concentrations. BN 52201 did not counteract the PAF action. The advantages of using sea urchins for PAF research in embryology are discussed.
本研究报告了血小板活化因子（PAF）对中间球海胆精子活力、受精及早期胚胎发育的影响。结果表明，PAF在10^(-8)-10^(-9) M浓度下可增强精子活力与受精能力，而在更高浓度时具有毒性。BN 52201不能拮抗PAF的作用。文中还讨论了利用海胆进行胚胎学中PAF研究的优势。
