Ko Y L, Lin J L, Lei M H, Chen J J, Tsou S S, Kuan P, Lien W P
Department of Internal Medicine, National Taiwan University Hospital, Taipei, Republic of China.
Cardiology. 1995;86(5):436-40. doi: 10.1159/000176917.
Apical segmental dysfunction is an unusual finding in hypertrophic cardiomyopathy (HCM). It is characterized by a poor clinical course and a high incidence of malignant ventricular tachyarrhythmias. Long-term prognosis of patients with HCM and apical segmental dysfunction is still unclear. We report 2 cases of apical segmental dysfunction in HCM in whom progressive apical dilatation and congestive heart failure developed. Both patients died suddenly, and intractable ventricular tachyarrhythmias were documented in 1 case during resuscitation. This report provides further evidence that apical segmental dysfunction might predict a subgroup of patients with HCM who are likely to develop end-stage heart failure and are at high risk of sudden cardiac death.
心尖段功能障碍在肥厚型心肌病（HCM）中是一种不常见的表现。其特点是临床病程不佳且恶性室性心律失常发生率高。HCM合并心尖段功能障碍患者的长期预后仍不明确。我们报告2例HCM合并心尖段功能障碍患者，这2例患者均出现进行性心尖部扩张和充血性心力衰竭。2例患者均猝死，其中1例在复苏过程中记录到顽固性室性心律失常。本报告进一步证明，心尖段功能障碍可能预示着HCM患者中的一个亚组，这些患者可能发展为终末期心力衰竭且心脏性猝死风险高。
