Hou A C, Chen J J, Jin Z P
Beijing Friendship Hospital.
Zhonghua Liu Xing Bing Xue Za Zhi. 1995 Aug;16(4):237-9.
In this study serum anti-urease antibodies of Helicobacter pylori was examined in order to investigate the prevalence of H. pylori infection in 394 children between age 1 and 13. The results showed that the average infection rate was 15.7% with a tendency of increase infection rate with age, and by the age of 12 the H. pylori infection rate reached 30%, which was higher than those found in developed countries. We also noticed that there was a comparatively higher serapositivity among 1 and 7 year olds. This may possibly be due to the close contact between family members and school mates. In addition, the serum positive rate of antibody to H. pylori urease in children with recurrent abdominal pain was much higher than those asymptomatic children (P < 0.05).
在本研究中，检测了幽门螺杆菌的血清抗脲酶抗体，以调查394名1至13岁儿童中幽门螺杆菌感染的患病率。结果显示，平均感染率为15.7%，且感染率有随年龄增长的趋势，到12岁时幽门螺杆菌感染率达到30%，高于发达国家的感染率。我们还注意到，1至7岁儿童的血清阳性率相对较高。这可能是由于家庭成员和同学之间的密切接触。此外，反复腹痛儿童的幽门螺杆菌脲酶抗体血清阳性率远高于无症状儿童（P<0.05）。
