受体酪氨酸激酶对Ras和其他信号通路的激活。 - Suppr

Suppr

超能文献

Activation of Ras and other signaling pathways by receptor tyrosine kinases.

作者信息

Schlessinger J, Bar-Sagi D

机构信息

Department of Pharmacology, New York University Medical Center, New York 10016, USA.

出版信息

Cold Spring Harb Symp Quant Biol. 1994;59:173-9. doi: 10.1101/sqb.1994.059.01.021.

DOI:10.1101/sqb.1994.059.01.021

PMID:7587067

Abstract

摘要

相似文献

Activation of Ras and other signaling pathways by receptor tyrosine kinases.受体酪氨酸激酶对Ras和其他信号通路的激活。

Cold Spring Harb Symp Quant Biol. 1994;59:173-9. doi: 10.1101/sqb.1994.059.01.021.

N-Shc: a neural-specific adapter molecule that mediates signaling from neurotrophin/Trk to Ras/MAPK pathway.N-Shc：一种神经特异性衔接分子，介导从神经营养因子/Trk到Ras/MAPK信号通路的信号传导。

Oncogene. 1996 Sep 19;13(6):1111-21.

Ion channels as physiological effectors for growth factor receptor and Ras/ERK signaling pathways.离子通道作为生长因子受体和Ras/ERK信号通路的生理效应器。

Adv Second Messenger Phosphoprotein Res. 1999;33:107-27. doi: 10.1016/s1040-7952(99)80007-x.

Inhibition of Caenorhabditis elegans vulval induction by gap-1 and by let-23 receptor tyrosine kinase.gap-1和let-23受体酪氨酸激酶对秀丽隐杆线虫外阴诱导的抑制作用。

Genes Dev. 1997 Oct 15;11(20):2715-28. doi: 10.1101/gad.11.20.2715.

Effect of herbimycin A on tyrosine kinase receptors and platelet derived growth factor (PDGF)-induced signal transduction.除莠霉素A对酪氨酸激酶受体及血小板衍生生长因子（PDGF）诱导的信号转导的影响。

Biol Pharm Bull. 1998 Oct;21(10):1030-5. doi: 10.1248/bpb.21.1030.

The SH2 and SH3 domain-containing protein GRB2 links receptor tyrosine kinases to ras signaling.

Cell. 1992 Aug 7;70(3):431-42. doi: 10.1016/0092-8674(92)90167-b.

Activation of EphA receptor tyrosine kinase inhibits the Ras/MAPK pathway.EphA受体酪氨酸激酶的激活会抑制Ras/丝裂原活化蛋白激酶（MAPK）信号通路。

Nat Cell Biol. 2001 May;3(5):527-30. doi: 10.1038/35074604.

Contribution of Src and Ras pathways in FGF-2 induced endothelial cell differentiation.Src和Ras信号通路在成纤维细胞生长因子-2诱导的内皮细胞分化中的作用

Oncogene. 1999 Jun 3;18(22):3354-64. doi: 10.1038/sj.onc.1202680.

Shc adaptor proteins are key transducers of mitogenic signaling mediated by the G protein-coupled thrombin receptor.Shc衔接蛋白是由G蛋白偶联凝血酶受体介导的促有丝分裂信号的关键转导分子。

EMBO J. 1996 Mar 1;15(5):1037-44.

Downregulation of the Ras-mitogen-activated protein kinase pathway by the EphB2 receptor tyrosine kinase is required for ephrin-induced neurite retraction.Ephrin诱导的神经突回缩需要EphB2受体酪氨酸激酶对Ras-丝裂原活化蛋白激酶途径进行下调。

Mol Cell Biol. 2001 Nov;21(21):7429-41. doi: 10.1128/MCB.21.21.7429-7441.2001.

引用本文的文献

Entabolons: How Metabolites Modify the Biochemical Function of Proteins and Cause the Correlated Behavior of Proteins in Pathways.代谢物组：代谢物如何改变蛋白质的生化功能并导致蛋白质在代谢途径中的相关行为。

J Chem Inf Model. 2025 Jun 9;65(11):5785-5800. doi: 10.1021/acs.jcim.5c00462. Epub 2025 May 16.

HB-EGF activates EGFR to induce reactive neural stem cells in the mouse hippocampus after seizures.HB-EGF 通过激活 EGFR 诱导癫痫后小鼠海马中的反应性神经干细胞。

Life Sci Alliance. 2024 Jul 8;7(9). doi: 10.26508/lsa.202201840. Print 2024 Sep.

Long Intergenic Non-Protein-Coding RNA 01138 Accelerates Tumor Growth and Invasion in Gastric Cancer by Regulating miR-1273e.长链非编码 RNA 01138 通过调控 miR-1273e 促进胃癌的生长和侵袭。

Med Sci Monit. 2019 Mar 23;25:2141-2150. doi: 10.12659/MSM.914248.

Regulatory mechanisms of branching morphogenesis in mouse submandibular gland rudiments.小鼠下颌下腺原基分支形态发生的调控机制。

Jpn Dent Sci Rev. 2018 Feb;54(1):2-7. doi: 10.1016/j.jdsr.2017.06.002. Epub 2018 Mar 17.

Proliferation and Survival of Embryonic Sympathetic Neuroblasts by MYCN and Activated ALK Signaling.MYCN和活化的ALK信号传导促进胚胎交感神经母细胞的增殖与存活。

J Neurosci. 2016 Oct 5;36(40):10425-10439. doi: 10.1523/JNEUROSCI.0183-16.2016.

Role of the IL-6-JAK1-STAT3-Oct-4 pathway in the conversion of non-stem cancer cells into cancer stem-like cells.IL-6-JAK1-STAT3-Oct-4 通路在非干细胞癌向癌干细胞样细胞转化中的作用。

Cell Signal. 2013 Apr;25(4):961-9. doi: 10.1016/j.cellsig.2013.01.007. Epub 2013 Jan 16.

Molecular mechanisms in signal transduction at the membrane.膜上信号转导的分子机制。

Nat Struct Mol Biol. 2010 Jun;17(6):659-65. doi: 10.1038/nsmb.1844. Epub 2010 May 23.

Towards a molecular understanding of the differential signals regulating alphabeta/gammadelta T lineage choice.朝着理解调节 αβ/γδ T 细胞谱系选择的差异信号的分子机制迈进。

Semin Immunol. 2010 Aug;22(4):237-46. doi: 10.1016/j.smim.2010.04.008. Epub 2010 May 14.

SSeCKS/Gravin/AKAP12 inhibits cancer cell invasiveness and chemotaxis by suppressing a protein kinase C- Raf/MEK/ERK pathway.SSeCKS/Gravin/AKAP12 通过抑制蛋白激酶 C-Raf/MEK/ERK 通路抑制癌细胞的侵袭和趋化性。

J Biol Chem. 2010 Feb 12;285(7):4578-86. doi: 10.1074/jbc.M109.073494. Epub 2009 Dec 15.

Brain-derived neurotrophic factor stimulates bone/cementum-related protein gene expression in cementoblasts.脑源性神经营养因子刺激成牙骨质细胞中骨/牙骨质相关蛋白基因的表达。

J Biol Chem. 2008 Jun 6;283(23):16259-67. doi: 10.1074/jbc.M800668200. Epub 2008 Apr 3.

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验