通过荧光原位杂交将免疫干扰素γ基因（IFNG）定位到染色体12q14带。
Mapping of the immune interferon gamma gene (IFNG) to chromosome band 12q14 by fluorescence in situ hybridization.
作者信息
Zimonjic D B, Rezanka L J, Evans C H, Polymeropoulos M H, Trent J M, Popescu N C
机构信息
Laboratory of Biology, National Cancer Institute, National Institutes of Health, Bethesda, MD 20892-4255, USA.
出版信息
Cytogenet Cell Genet. 1995;71(3):247-8. doi: 10.1159/000134119.
The human immune interferon gamma gene (IFNG) was localized to chromosome band 12q14 by fluorescence in situ hybridization. This correction of a previous localization resolves the discrepancy between the syntenic maps of human chromosome 12 and mouse chromosome 10 and facilitates linkage analysis and identification of gene interactions near this region of chromosome 12 as well as further genetic studies of interferon-gamma immune-associated diseases.
通过荧光原位杂交技术，人类免疫干扰素γ基因（IFNG）被定位到染色体12q14带。这一先前定位的修正解决了人类12号染色体与小鼠10号染色体同线图谱之间的差异，便于进行连锁分析以及识别12号染色体该区域附近的基因相互作用，还利于对干扰素γ免疫相关疾病开展进一步的遗传学研究。
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