Niu Y, Fan Y, Fu X
Tianjin Cancer Hospital and Institute.
Zhonghua Zhong Liu Za Zhi. 1995 Jul;17(4):298-300.
In mastectomy specimens, the primary foci of occult breast carcinoma were examinated usually by routine histopathological method, but the result was not satisfactory. The detecting rates of primary foci were 50%-56% in China and 45%-75% in some other countries. In this study, whole organ subserial section was performed in 20 cases of occult breast cancer from April, 1988 to February, 1994. Primary foci were found in 16 cases (80%) by microscopic examination. Diameters of 10 foci were less than 1.0cm and the smallest one was 0.3 x 0.1 x 0.1cm. In addition, occult breast cancer with multiple foci was detected in 5 cases (31.25%), which would be very difficult to be found by routine histopathological examination. The possible causes for the failure of detection of the primary foci on whole organ section are discussed.
在乳房切除术标本中，隐匿性乳腺癌的原发灶通常采用常规组织病理学方法进行检查，但结果并不理想。在中国，原发灶的检出率为50% - 56%，在其他一些国家为45% - 75%。本研究对1988年4月至1994年2月间的20例隐匿性乳腺癌患者进行了全器官连续切片检查。经显微镜检查，16例（80%）发现了原发灶。10个病灶的直径小于1.0cm，最小的一个为0.3×0.1×0.1cm。此外，5例（31.25%）检测到多灶性隐匿性乳腺癌，这通过常规组织病理学检查很难发现。文中讨论了全器官切片时原发灶检测失败的可能原因。
