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酒精耐受性降低:在酒精依赖中的临床意义

Decrease in alcohol tolerance: clinical significance in alcohol dependence.

作者信息

Ziółkowski M, Maludzińska E, Gruss T, Rybakowski J, Volpicelli J R

机构信息

Department of Psychiatry, Medical Academy, Bydgoszcz, Poland.

出版信息

Drug Alcohol Depend. 1995 Jul;39(1):33-6. doi: 10.1016/0376-8716(95)01131-h.

DOI:10.1016/0376-8716(95)01131-h
PMID:7587972
Abstract

In 237 male inpatients with alcohol dependence, clinical, demographic and biochemical data were analyzed in relation to alcohol tolerance. All subjects had a history of marked tolerance. At the time of assessment, 46% of subjects continued to meet the criteria for marked tolerance and 54% of the subjects reported a loss or decreased tolerance. Subjects with decreased tolerance were older than those with high tolerance and had a longer duration of illness. The age of onset was similar in both groups. Patients with decreased tolerance had more mental confusion and psychotic symptoms, and were less likely to be currently married.

摘要

对237名酒精依赖男性住院患者的临床、人口统计学和生化数据进行了与酒精耐受性相关的分析。所有受试者都有明显耐受性的病史。在评估时,46%的受试者仍符合明显耐受性的标准,54%的受试者报告耐受性丧失或降低。耐受性降低的受试者比耐受性高的受试者年龄更大,病程更长。两组的发病年龄相似。耐受性降低的患者有更多的精神错乱和精神病症状,目前结婚的可能性较小。

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