Gorman M, Barkley G L
Department of Neurology, Henry Ford Hospital, Detroit, Michigan 48202, USA.
Epilepsia. 1995 Nov;36(11):1158-60. doi: 10.1111/j.1528-1157.1995.tb00477.x.
A 32-year-old man with mental retardation and uncontrolled complex partial epilepsy receiving carbamazepine (CBZ) and divalproex sodium (VPA), developed frequent episodes of forced upward gaze after increase in the daily VPA dosage. CBZ dosage was decreased, with prompt resolution of symptoms. The upward gaze problem recurred several months later. CBZ dosage was decreased further with subsequent resolution of symptoms. Therefore, the oculogyric crisis (OGC) appeared to be induced by CBZ.
一名32岁患有智力障碍且复杂性部分性癫痫控制不佳的男性,正在服用卡马西平(CBZ)和丙戊酸钠(VPA),在每日VPA剂量增加后出现频繁的强迫性上视发作。降低了CBZ剂量后,症状迅速缓解。几个月后上视问题再次出现。进一步降低CBZ剂量后症状随后得到缓解。因此,动眼危象(OGC)似乎是由CBZ诱发的。