An examination of the potential "genotoxic" carcinogenicity of a biopesticide derived from the neem tree.
作者信息
Rosenkranz H S, Klopman G
机构信息
Department of Environmental and Occupational Health, University of Pittsburgh, Pennsylvania 15238, USA.
出版信息
Environ Mol Mutagen. 1995;26(3):255-60. doi: 10.1002/em.2850260311.
PMID:7588652
Abstract
Structural analyses of azadirachtin, a promising biopesticide recently introduced into the United States, indicates that this natural product has the potential for acting as a "genotoxic" carcinogen. In view of the fact that genotoxic carcinogens are regarded as presenting a potential carcinogenic risk to humans, the present finding suggests that the possible metabolism of azadirachtin to DNA-reactive products be evaluated experimentally.
摘要
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