Rosenkranz H S, Klopman G
Department of Environmental and Occupational Health, University of Pittsburgh, Pennsylvania 15238, USA.
Environ Mol Mutagen. 1995;26(3):255-60. doi: 10.1002/em.2850260311.
Structural analyses of azadirachtin, a promising biopesticide recently introduced into the United States, indicates that this natural product has the potential for acting as a "genotoxic" carcinogen. In view of the fact that genotoxic carcinogens are regarded as presenting a potential carcinogenic risk to humans, the present finding suggests that the possible metabolism of azadirachtin to DNA-reactive products be evaluated experimentally.
