Fonkalsrud E W
Arch Surg. 1979 Jan;114(1):48-51. doi: 10.1001/archsurg.1979.01370250050010.
Esophageal dysmotility and gastroesophageal reflux (GER) are common sequelae that may persist for many years in infants and children who have undergone repair of esophageal atresia and tracheoesophageal fistula (TEF). The slow clearance of refluxed gastric contents appears to cause a high incidence of aspiration, a high incidence of esophageal anastomotic stricture or leak, and a slow response to dilation of esophageal anastomotic strictures. Nissen transabdominal gastroesophageal fundoplication was performed in nine children (seven who were less than 4 months of age) subsequent to repair of esophageal atresia because of recurrent severe symptoms due to regurgitation. On the basis of this favorable experience with nine infants and children, we believe that an aggressive surgical approach should be taken in the management of symptomatic GER in patients at a young age following repair of esophageal atresia and TEF who fail to respond to an adequate trial of medical treatment.
食管运动功能障碍和胃食管反流(GER)是常见的后遗症,在接受食管闭锁和气管食管瘘(TEF)修复术的婴幼儿中可能会持续多年。反流的胃内容物清除缓慢似乎导致误吸发生率高、食管吻合口狭窄或漏的发生率高,以及食管吻合口狭窄扩张反应缓慢。由于反流导致反复出现严重症状,9名儿童(7名年龄小于4个月)在食管闭锁修复术后接受了经腹Nissen胃底折叠术。基于对9名婴幼儿的良好经验,我们认为,对于食管闭锁和TEF修复术后出现症状性GER且对充分的药物治疗试验无反应的年轻患者,应采取积极的手术方法进行治疗。