Niimi A, Amitani R, Ikeda T, Kubo Y, Tanaka E, Kuze F
Dept of Infection and Inflammation, Kyoto University, Japan.
Eur Respir J. 1995 Jul;8(7):1237-9. doi: 10.1183/09031936.95.08071237.
In a 50 year old man who complained of cough and sputum, a small endobronchial tumour was found in the left main bronchus and was biopsied via bronchoscopy. The histological diagnosis was inflammatory polyp with marked infiltration of eosinophils. Six years later, the patient developed asthma. At the same time, another polyp was found in the posterior basal bronchus of the right lower lobe. The appearance of the first polyp was unchanged endoscopically and histologically. Inhalation of beclomethasone dipropionate, 200 micrograms b.i.d., was started and symptoms of asthma soon subsided. In addition, the two polyps regressed and eventually disappeared after one year of treatment. Inhaled corticosteroids, being noninvasive and relatively safe, appear to be a possible therapeutic option in inflammatory bronchial polyps, especially in cases where the patient has asthma as an underlying condition, or the polyps are small and their management is not urgent.
一名50岁男性主诉咳嗽、咳痰，在左主支气管发现一个小的支气管内肿瘤，通过支气管镜进行活检。组织学诊断为炎性息肉，伴有明显的嗜酸性粒细胞浸润。6年后，该患者出现哮喘。与此同时，在右下叶后基底支气管发现另一个息肉。第一个息肉的外观在内镜和组织学上均无变化。开始吸入丙酸倍氯米松，每次200微克，每日两次，哮喘症状很快缓解。此外，两个息肉在治疗一年后消退并最终消失。吸入性糖皮质激素无创且相对安全，似乎是炎性支气管息肉的一种可能治疗选择，尤其是在患者有哮喘基础疾病，或息肉较小且处理不紧急的情况下。
