供体白细胞层输注与化疗用于骨髓移植后复发的白血病
Donor buffy-coat infusion and chemotherapy for leukemia in relapse after marrow transplantation.
作者信息
Bogdanić V, Aurer I, Hitrec V, Boban D, Nemet D, Zupancić-Salek S, Labar B
机构信息
Department of Internal Medicine, Medical School, Zagreb, Croatia.
出版信息
Haematologica. 1995 Jul-Aug;80(4):338-40.
A patient relapsing with blastic lymphoid transformation of chronic myeloid leukemia after bone marrow transplantation received donor buffy-coat infusion. Low-dose chemotherapy was added because of a rapid WBC increase. Complete hematologic and cytogenetic remission was obtained. The patient remained in complete hematologic and cytogenetic remission for four months until he died in an accident. Two patients with acute leukemia failed to respond to a similar treatment.
一名慢性髓性白血病患者在骨髓移植后发生原始淋巴细胞转化复发，接受了供体白细胞层输注。由于白细胞迅速增加，加用了小剂量化疗。获得了完全血液学和细胞遗传学缓解。该患者保持完全血液学和细胞遗传学缓解达四个月，直至死于一场事故。两名急性白血病患者对类似治疗无反应。
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