Chatterjee S S, Pahari D K, Sharma R K, Halder B, Roy S, Ghosh S, Biswas P, Banerjee A, Khan A, Mukherjee S
Department of Cardiology, Institute of Postgraduate Medical Education & Research, Calcutta.
Indian Heart J. 1995 Mar-Apr;47(2):120-4.
Percutaneous transluminal renal angioplasty (PTRA) was attempted in 96 patients of renovascular hypertension (RVHT) admitted during the period 1986 to 1992. The patients' age ranged from 14-70 (mean: 38.7 +/- 18.8) years. There were 42 (43.8%) males and 54 (56.2%) females. The cause of renal artery stenosis (RAS) was aorto-arteritis in 44 (45.8%), atherosclerosis in 28 (29.2%) and fibromuscular dysplasia in 24 (25%). Bilateral RAS was found in 16 (16.7%). PTRA was angiographically successful in 92 (95.8%) patients. The mean pressure gradient decreased from 82.6 +/- 8.2 to 11.2 +/- 3.6 mm Hg in aorto-arteritis, 75.2 +/- 13.2 to 9.6 +/- 6.4 mm Hg in atherosclerosis and from 86.4 +/- 10.6 to 13.2 +/- 8.2 mm Hg in fibromuscular dysplasia respectively. The patients were followed up for 43.2 +/- 24.1 (range: 6-77) months. Remission or satisfactory lowering of blood pressure was achieved in 80 (86.9%) patients. Clinical success rate (remission or satisfactory lowering of BP) at the end of follow-up period was 75.3 percent. Randomly selected repeat angiography was done in 45 out of 92 (49.1%) patients at the end of 24 months of follow-up. Restenosis was detected in 12 (26.7%) patients and was commonest in the atherosclerotic group (42.8%), followed by fibromuscular dysplasia (14.3%) and least common in aorto-arteritis (11.8%). Repeat angioplasty was done successfully in 10 (83.3%) patients.(ABSTRACT TRUNCATED AT 250 WORDS)
1986年至1992年期间,对收治的96例肾血管性高血压(RVHT)患者尝试进行经皮腔内肾血管成形术(PTRA)。患者年龄在14至70岁之间(平均:38.7±18.8岁)。男性42例(43.8%),女性54例(56.2%)。肾动脉狭窄(RAS)的病因中,大动脉炎44例(45.8%),动脉粥样硬化28例(29.2%),纤维肌性发育异常24例(25%)。发现双侧RAS 16例(16.7%)。92例(95.8%)患者PTRA血管造影成功。大动脉炎患者平均压力阶差从82.6±8.2降至11.2±3.6 mmHg,动脉粥样硬化患者从75.2±13.2降至9.6±6.4 mmHg,纤维肌性发育异常患者从86.4±10.6降至13.2±8.2 mmHg。对患者随访43.2±24.1(范围:6至77)个月。80例(86.9%)患者血压缓解或满意降低。随访期末临床成功率(血压缓解或满意降低)为75.3%。92例患者中有45例(49.1%)在随访24个月结束时随机进行了重复血管造影。12例(26.7%)患者检测到再狭窄,最常见于动脉粥样硬化组(42.8%),其次是纤维肌性发育异常组(14.3%),最少见于大动脉炎组(11.8%)。10例(83.3%)患者重复血管成形术成功。(摘要截短至250字)