Tan U
Atatürk University, Medical Faculty, Department of Physiology, Erzurum, Turkey.
Int J Neurosci. 1995 May;82(1-2):105-11. doi: 10.3109/00207459508994294.
Since there is no theological explanation for high growth hormone (GH) concentrations in perinatal blood, GH concentrations from umbilical cord blood were studied in relation to body weight and head circumference (brain weight) in the human neonates. GH exhibited inverse correlations with body weight and head circumference in these subjects, which depended upon sex, familial sinistrality (FS), and grasp-reflex dominance. This implies that GH may adversely influence the brain/body development during perinatal development on the basis of a genetically predetermined brain organization. It was suggested that the lipolytic and anti-insulin GH effects may be responsible for its body-weight reducing effects; the anti-insulin GH actions may be responsible for its brain-weight reducing effects. As a result of these actions, GH may limit the brain/body development, to induce a balanced growth during perinatal period.
由于围产期血液中生长激素（GH）浓度较高尚无神学解释，因此对人类新生儿脐带血中的GH浓度与体重和头围（脑重）的关系进行了研究。在这些研究对象中，GH与体重和头围呈负相关，这取决于性别、家族性左利手（FS）和抓握反射优势。这意味着GH可能在基于基因预先确定的脑组织结构的围产期发育过程中对脑/体发育产生不利影响。有人提出，GH的脂解和抗胰岛素作用可能是其减轻体重作用的原因；GH的抗胰岛素作用可能是其减轻脑重作用的原因。由于这些作用，GH可能会限制脑/体发育，以在围产期诱导平衡生长。
