Prikazska M, Simoncic R
Research Institute of Nutrition, Bratislava, Slovakia.
Isr J Med Sci. 1995 Nov;31(11):681-4.
Autonomic neuropathy (AN) is more common than previously presumed. In this paper we focus on these changes in the esophagus, which are the most common but clinically the least symptomatic. We examined 36 non-obese subjects with previously diagnosed peripheral neuropathy with no or only mild subjective complaints. Cardiorespiratory tests revealed signs of AN in 93% of the cases. Cholinergic changes were found in 20 patients, 7 of whom also had adrenergic changes. Radiographic changes included: tertiary spasms in 16.7%, inert esophagus in 5.5%, and gastro-esophageal reflex in 5.5% of patients. Statistically significant differences in the passage rate (P < 0.01) and in the lumen of esophagus (P < 0.001) were also found. Mean values obtained in the control group were considered as baseline.
自主神经病变（AN）比之前推测的更为常见。在本文中，我们重点关注食管的这些变化，它们最为常见，但在临床上症状最少。我们检查了36名先前被诊断为周围神经病变的非肥胖受试者，他们没有或仅有轻微的主观症状。心肺测试显示93%的病例有AN的迹象。在20名患者中发现了胆碱能变化，其中7名患者也有肾上腺素能变化。影像学变化包括：16.7%的患者出现第三期痉挛，5.5%的患者食管无蠕动，5.5%的患者出现胃食管反流。还发现通过率（P < 0.01）和食管管腔（P < 0.001）有统计学显著差异。将对照组获得的平均值视为基线。
