Bałkowiec A, Szulczyk P
Katedra i Zakład Fizjologii Człowieka Akademii Medycznej w Warszawie, Poland.
J Appl Physiol (1985). 1995 Aug;79(2):594-9. doi: 10.1152/jappl.1995.79.2.594.
The pattern of response of 45 single postganglionic sympathetic axons dissected from the right recurrent laryngeal nerve was examined in chloralose-anesthetized cats. Both vagoaortic nerves were cut, and both sinus nerves were left intact. Each neuron, based on the presence of cardiac and respiratory rhythmicities in its resting activity and reaction to systemic hypoxia (10% O2 in N2 for 2 min), was classified into one of three classes. Class I neurons (n = 29, 64%) were activated during systemic hypoxia and had a pronounced cardiac and inspiration-related rhythmicity in their resting activity. Class II neurons (n = 12,27%) were inhibited during systemic hypoxia, and their cardiac and respiratory rhythmicities were either negligible or totally absent. Class III neurons (n = 4,9%), similarly to class I, had a pronounced cardiac and inspiratory rhythmicity but were not affected by systemic hypoxia. The systemic hypoxia was always accompanied by an increase in blood pressure. We conclude that class I and possibly class III neurons innervate the arteries of upper airways. We also discuss the possibility that class II neurons are responsible for regulating the smooth muscles of upper airways.
在水合氯醛麻醉的猫身上，检查了从右侧喉返神经分离出的45条节后交感单轴突的反应模式。双侧迷走主动脉神经被切断，双侧窦神经保持完整。根据每个神经元静息活动中心脏和呼吸节律的存在情况以及对全身性缺氧（氮气中10%氧气，持续2分钟）的反应，将其分为三类中的一类。I类神经元（n = 29，64%）在全身性缺氧时被激活，其静息活动中有明显的与心脏和吸气相关的节律。II类神经元（n = 12，27%）在全身性缺氧时受到抑制，其心脏和呼吸节律要么可忽略不计，要么完全不存在。III类神经元（n = 4，9%）与I类神经元相似，有明显的心脏和吸气节律，但不受全身性缺氧影响。全身性缺氧总是伴随着血压升高。我们得出结论，I类神经元以及可能的III类神经元支配上呼吸道的动脉。我们还讨论了II类神经元负责调节上呼吸道平滑肌的可能性。
