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肾移植患者体外受精后成功的妊娠结局。

Successful pregnancy outcome in a renal transplant patient following in-vitro fertilization.

作者信息

Lockwood G M, Ledger W L, Barlow D H

机构信息

Nuffield Department of Obstetrics and Gynaecology, John Radcliffe Hospital, Oxford, UK.

出版信息

Hum Reprod. 1995 Jun;10(6):1528-30. doi: 10.1093/humrep/10.6.1528.

DOI:10.1093/humrep/10.6.1528
PMID:7593529
Abstract

Renal transplantation transforms the fertility potential of women with end-stage renal failure and the prognosis for both pregnancy outcome and continuing renal function in those patients is generally good. Currently one in 50 women become pregnant following renal transplant and it may be assumed that more would welcome the chance of biological parenthood if their fertility problems, related often to tubal damage, could be overcome. We here report our experience of treating a couple with secondary infertility with in-vitro fertilization and embryo transfer where the wife is a renal transplant recipient. We believe this is the first reported case.

摘要

肾移植改变了终末期肾衰竭女性的生育潜能,这些患者的妊娠结局及肾功能持续情况总体良好。目前,每50名肾移植后的女性中就有1人怀孕,并且可以推测,如果她们常因输卵管损伤而导致的生育问题能够得到解决,会有更多女性渴望拥有亲生子女。我们在此报告对一对继发性不孕夫妇进行体外受精和胚胎移植的治疗经验,该妻子是肾移植受者。我们认为这是首例报道病例。

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引用本文的文献

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BMC Nephrol. 2025 Jul 5;26(1):355. doi: 10.1186/s12882-025-04285-y.
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Pregnancy Outcomes Using Assisted Reproductive Technology in Kidney Transplant Recipients.肾移植受者使用辅助生殖技术的妊娠结局
Transplantation. 2025 Jul 4. doi: 10.1097/TP.0000000000005449.
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Pregnancy after kidney transplantation: an observational study on maternal, graft and offspring outcomes in view of current literature.
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Front Nephrol. 2023 Jul 27;3:1216762. doi: 10.3389/fneph.2023.1216762. eCollection 2023.
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J Clin Med. 2022 Aug 16;11(16):4792. doi: 10.3390/jcm11164792.
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