Fargnoli M C, Bolognia J L
Department of Dermatology, University of L'Aquila, Italy.
J Am Acad Dermatol. 1995 Nov;33(5 Pt 2):853-6. doi: 10.1016/0190-9622(95)90422-0.
The term "trichrome vitiligo" has been used to describe lesions of vitiligo that have an intermediate level of color between the achromic center and the peripheral unaffected skin. We describe a 12-year-old black girl with a generalized pigmentary disorder that first appeared when she was 3 years of age. Five shades of colors--white, tan, medium brown (unaffected skin), dark brown, and black--were present. Biopsy specimens of the depigmented areas showed a complete absence of melanocytes, whereas the most hyperpigmented areas were characterized by an increase in epidermal pigment and number of melanocytes. The lack of any preceding inflammation in the affected areas and the subsequent widespread spontaneous depigmentation that occurred within 1 year pointed to a diagnosis of "pentachrome vitiligo."
术语“三色白癜风”已被用于描述白癜风皮损，其在无色素中心与周边未受累皮肤之间具有中间颜色水平。我们描述了一名12岁的黑人女孩，她患有全身性色素沉着紊乱，3岁时首次出现。皮损有五种颜色——白色、棕褐色、中棕色（未受累皮肤）、深棕色和黑色。色素脱失区域的活检标本显示黑素细胞完全缺失，而色素沉着最明显的区域表现为表皮色素增加和黑素细胞数量增多。受累区域缺乏任何先前的炎症，且在1年内出现随后广泛的自发性色素脱失，提示诊断为“五色白癜风”。
