Thomas A, Hari L, Nagarajan M, Prabhakar R
Tuberculosis Research Centre, Madras, India.
Int J Lepr Other Mycobact Dis. 1995 Sep;63(3):391-4.
A controlled clinical trial in highly bacilliferous multibacillary leprosy patients was initiated in 1977. We report here two cases of relapse during long-term follow up of patients 15 years after the start of treatment. The patients reported here were treated with rifampin, isoniazid, clofazimine and dapsone for the first 3 months followed by clofazimine and dapsone until 84 months in one case; the other case received the same treatment but had received dapsone alone for 60-80 months. The relapses occurred 6(1/2) 7(1/2) years after therapy was discontinued.
1977年启动了一项针对高菌量多菌型麻风病患者的对照临床试验。我们在此报告两例患者在治疗开始15年后长期随访期间复发的病例。此处报告的患者最初3个月接受利福平、异烟肼、氯法齐明和氨苯砜治疗，之后一例患者接受氯法齐明和氨苯砜治疗直至84个月；另一例患者接受相同治疗，但单独服用氨苯砜60 - 80个月。复发发生在停药后6（1/2）至7（1/2）年。
