Harat M, Radek A, Błaszczyk B, Maciejczak A, Piwowarski W
Kliniki Neurochirurgii WAM w Lodzi.
Neurol Neurochir Pol. 1995 Jan-Feb;29(1):45-52.
The authors present diagnostic problem in slowly growing brain gliomas. Two illustrative cases are presented. Both were characterized by scant clinical manifestations and long-term course of the illness before the operation. CT examinations repeated in both patients several times in the preoperative period of a few years disclosed unchanging hypodense areas in cerebral hemispheres. No progress in clinical status of the patients and CT imaging of the lesions were observed throughout years of observation (2 and 5 years, respectively). Rapid deterioration of neurological condition in both patients associated with enlargement of the lesions in CT allowed to establish strong suspicion of brain tumour which was confirmed by examination in each case. Histopathological examination revealed malignant gliomas in both cases. The cases confirmed once again the necessity of early MRI examination in patients with hypodense lesions of the brain found in CT. The authors believe that every hypodense area of the brain should be verified by MRI as soon as possible, regardless their size, progress and neurological status of the patient. Such as approach to the diagnosis of hypodense areas in the CT of the brain may prevent a delay in proper treatment as well as malignant transformation of primarily benign lesion.
作者介绍了生长缓慢的脑胶质瘤的诊断问题。文中展示了两个典型病例。二者的特点均为临床表现轻微且术前病程长。在术前几年里,两名患者均多次进行CT检查,结果显示脑半球存在无变化的低密度区。在长达数年(分别为2年和5年)的观察期内,患者的临床状况和病变的CT影像均无进展。两名患者的神经状况迅速恶化,同时CT显示病变增大,这使得医生高度怀疑脑肿瘤,而后续检查证实了这一怀疑。组织病理学检查显示,两例均为恶性胶质瘤。这两个病例再次证实,对于CT发现的脑低密度病变患者,早期进行MRI检查很有必要。作者认为,无论脑低密度区的大小、进展情况以及患者的神经状况如何,都应尽快通过MRI进行核实。这种针对脑CT中低密度区的诊断方法可以避免延误恰当治疗以及原发性良性病变的恶性转化。