Virata S R, Kylstra J A, Peiffer R L
Department of Ophthalmology, University of North Carolina, Chapel Hill 27599-7040, USA.
Ophthalmic Surg. 1995 Mar-Apr;26(2):142-4.
Optimal treatment of intralenticular metallic foreign-body injuries remains controversial, especially in patients with clear lenses and good vision. Using 20 rabbit eyes, we examined the cataractogenic potential of intralenticular iron and its effects on the retina. Iron wire implanted into the lenses of 12 rabbit eyes caused cataracts in every eye within 4 weeks. However, after 4 1/2 weeks, none of these eyes showed evidence of retinal siderosis. No cataracts developed in five eyes with intralenticular glass, while three with intravitreal iron showed marked retinal toxicity. These results suggest that as long as the lenses remain clear, conservative management of these injuries carries minimal risk of permanent retinal damage.
晶状体内部金属异物损伤的最佳治疗方法仍存在争议，尤其是对于晶状体透明且视力良好的患者。我们使用20只兔眼，研究了晶状体内部铁的致白内障潜力及其对视网膜的影响。将铁丝植入12只兔眼的晶状体后，每只眼睛在4周内均出现白内障。然而，在4.5周后，这些眼睛均未显示出视网膜铁质沉着的迹象。5只植入晶状体内部玻璃的眼睛未形成白内障，而3只玻璃体内植入铁的眼睛则表现出明显的视网膜毒性。这些结果表明，只要晶状体保持透明，对这些损伤进行保守治疗导致永久性视网膜损伤的风险极小。
