Romics I, Bocsi J, Bach D, Beutler W, Kopper L, Frang D
Semmelweis Orvostudományi Egyetem Urológiai Klinika.
Orv Hetil. 1995 Jun 18;136(25):1323-7.
Biological behavior of prostatic cancer is influenced by different tumor factors. The proliferative activity of the malignancies could be one of those parameters which serve as basis to design therapy and to estimate prognosis. Here ploidity and S-phase fraction of 44 prostatic cancer obtained by radical prostatectomy were compared to other known tumor characteristics (PSA, staging, grading). There are correlations between the PSA concentration, grading, staging and S phase fraction. The ploidity correlates with the grading. Neither of kinetic parameter correlated with the nodal involvement.
前列腺癌的生物学行为受不同肿瘤因素影响。恶性肿瘤的增殖活性可能是作为设计治疗方案和评估预后基础的参数之一。在此,将44例经根治性前列腺切除术获得的前列腺癌的倍体和S期分数与其他已知肿瘤特征(前列腺特异性抗原、分期、分级)进行比较。前列腺特异性抗原浓度、分级、分期与S期分数之间存在相关性。倍体与分级相关。动力学参数均与淋巴结受累无关。