阿司匹林及相关非甾体抗炎药作为结肠癌的化学预防剂。 - Suppr

Aspirin and related nonsteroidal anti-inflammatory drugs as chemopreventive agents against colon cancer.

作者信息

Marnett L J

机构信息

A.B. Hancock Jr. Memorial Laboratory for Cancer Research, Department of Biochemistry, Vanderbilt University School of Medicine, Nashville, Tennessee 37232, USA.

出版信息

Prev Med. 1995 Mar;24(2):103-6. doi: 10.1006/pmed.1995.1017.

DOI:10.1006/pmed.1995.1017

PMID:7597006

Abstract

摘要

相似文献

Prev Med. 1995 Mar;24(2):103-6. doi: 10.1006/pmed.1995.1017.

The role of arachidonic acid regulatory enzymes in colorectal disease.花生四烯酸调节酶在结直肠疾病中的作用。

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Is inhibition of cyclooxygenase required for the chemopreventive effect of NSAIDs in colon cancer? A model reconciling the current contradiction.非甾体抗炎药（NSAIDs）对结肠癌的化学预防作用是否需要抑制环氧化酶？一个调和当前矛盾的模型。

Med Hypotheses. 2000 Feb;54(2):210-5. doi: 10.1054/mehy.1999.0023.

Novel approaches for colon cancer prevention by cyclooxygenase-2 inhibitors.环氧合酶-2抑制剂预防结肠癌的新方法。

J Environ Pathol Toxicol Oncol. 2002;21(2):155-64.

An introduction to aspirin, NSAids, and COX-2 inhibitors for the primary prevention of cardiovascular events and cancer and their potential preventive role in bladder carcinogenesis: part II.阿司匹林、非甾体抗炎药和COX - 2抑制剂在心血管事件和癌症一级预防中的介绍及其在膀胱癌发生中的潜在预防作用：第二部分。

Semin Urol Oncol. 2001 Nov;19(4):306-16.

Non-COX-2 targets and cancer: expanding the molecular target repertoire of chemoprevention.非环氧化酶-2靶点与癌症：拓展化学预防的分子靶点库

Biochem Pharmacol. 2005 Oct 1;70(7):969-86. doi: 10.1016/j.bcp.2005.05.004.

Studies with the azoxymethane-rat preclinical model for assessing colon tumor development and chemoprevention.使用偶氮甲烷大鼠临床前模型评估结肠肿瘤发展和化学预防的研究。

Environ Mol Mutagen. 2004;44(1):26-35. doi: 10.1002/em.20026.

[Cyclo-oxygenase 2 in cancer].[癌症中的环氧化酶2]

Duodecim. 1999;115(8):855-6.

Chemopreventive properties of a selective inducible nitric oxide synthase inhibitor in colon carcinogenesis, administered alone or in combination with celecoxib, a selective cyclooxygenase-2 inhibitor.一种选择性诱导型一氧化氮合酶抑制剂在结肠癌发生过程中的化学预防特性，单独给药或与选择性环氧化酶-2抑制剂塞来昔布联合给药时的情况。

Cancer Res. 2002 Jan 1;62(1):165-70.

Differential inhibition of murine prostaglandin synthase-1 and -2 by nonsteroidal anti-inflammatory drugs using exogenous and endogenous sources of arachidonic acid.使用花生四烯酸的外源性和内源性来源，非甾体抗炎药对小鼠前列腺素合酶-1和-2的差异性抑制作用。

J Pharmacol Exp Ther. 1997 Feb;280(2):606-13.

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Aspirin Use, Compliance, and Knowledge of Anticancer Effect in the Community.阿司匹林的使用、依从性和对其抗癌作用的认知在社区中的情况。

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Sterically stabilized liposomes incorporating the novel anticancer agent phospho-ibuprofen (MDC-917): preparation, characterization, and in vitro/in vivo evaluation.载新型抗癌药物磷酸布洛芬（MDC-917）的立体稳定脂质体的制备、表征及体外/体内评价。

Pharm Res. 2012 Jun;29(6):1435-43. doi: 10.1007/s11095-011-0619-y. Epub 2011 Nov 10.

Phospho-ibuprofen (MDC-917) is a novel agent against colon cancer: efficacy, metabolism, and pharmacokinetics in mouse models.磷酸布洛芬（MDC-917）是一种新型结肠癌治疗药物：在小鼠模型中的疗效、代谢和药代动力学。

J Pharmacol Exp Ther. 2011 Jun;337(3):876-86. doi: 10.1124/jpet.111.180224. Epub 2011 Mar 21.

The role of translational regulation in ultraviolet C light-induced cyclooxygenase-2 expression.翻译调控在紫外线C光诱导的环氧合酶-2表达中的作用。

Life Sci. 2009 Jul 3;85(1-2):70-6. doi: 10.1016/j.lfs.2009.04.018. Epub 2009 May 5.

Suppression by nimesulide of bombesin-enhanced peritoneal metastasis of intestinal adenocarcinomas induced by azoxymethane in Wistar rats.

Clin Exp Metastasis. 2003;20(6):555-60. doi: 10.1023/a:1025883129932.

Cooperative effects of matrix metalloproteinase and cyclooxygenase-2 inhibition on intestinal adenoma reduction.

Br J Cancer. 2003 May 6;88(9):1445-52. doi: 10.1038/sj.bjc.6600867.

Regular aspirin use and lung cancer risk.定期服用阿司匹林与肺癌风险

BMC Cancer. 2002 Nov 26;2:31. doi: 10.1186/1471-2407-2-31.

Regular use of aspirin and pancreatic cancer risk.阿司匹林的常规使用与胰腺癌风险

BMC Public Health. 2002 Sep 4;2:18. doi: 10.1186/1471-2458-2-18.

Nonsteroidal anti-inflammatory drugs and prevention of colorectal cancer.非甾体抗炎药与结直肠癌的预防

Curr Gastroenterol Rep. 1999 Oct;1(5):441-8. doi: 10.1007/s11894-999-0027-1.

Cyclooxygenase-2 overexpression correlates with tumour recurrence, especially haematogenous metastasis, of colorectal cancer.环氧化酶-2的过表达与结直肠癌的肿瘤复发尤其是血行转移相关。

Br J Cancer. 2000 Aug;83(3):324-8. doi: 10.1054/bjoc.2000.1270.

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Aspirin and related nonsteroidal anti-inflammatory drugs as chemopreventive agents against colon cancer.

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