Brüning R, Danek A
Institut für Radiologische Diagnostik, Ludwig-Maximilians-Universität München, Klinikum Grosshadern.
Radiologe. 1995 Apr;35(4):256-62.
Functional magnetic resonance imaging (MRI) allows to directly visualize regional activity of the visual cortex during stimulation. The value of the method to evaluate physiologic and pathologic conditions is elaborated on in comparison with positron emission tomography (PET). Aspects as sequence selection and stimulus paradigms are discussed. Subtle activity in the primary cortex (V1), processing areas as MT/V5 and subcortical areas are visualized by MRI. Cooperation of the subjects is a essential factor. Despite promising initial results in clinical trials the focus of research in clinical trials the focus of research in the visual cortex yet remains in the preclinical field.
功能磁共振成像(MRI)能够在刺激过程中直接观察视觉皮层的局部活动。与正电子发射断层扫描(PET)相比,阐述了该方法在评估生理和病理状况方面的价值。讨论了序列选择和刺激范式等方面。MRI可显示初级皮层(V1)、MT/V5等处理区域以及皮层下区域的细微活动。受试者的配合是一个关键因素。尽管在临床试验中取得了令人鼓舞的初步结果,但视觉皮层的临床试验研究重点仍停留在临床前领域。