[血清阳性感染个体中的抗人嗜T淋巴细胞病毒I型抗体滴度]
[Anti HTLV-I antibody titers in seropositive infected individuals].
作者信息
Galeno H, Ramírez E, Mora J, Ojeda M, Cartier L
机构信息
Centro Nacional de Referencia del SIDA (CNRS), Sección Virología, Instituto de Salud Pública de Chile.
出版信息
Rev Med Chil. 1994 Sep;122(9):1004-7.
The aim of this study was to determine anti HTLV-I antibody titers in seropositive symptomatic and asymptomatic infected subjects. One hundred seven infected subjects (47 with spastic paraparesis and 60 asymptomatic) were studied. HTLV-I antibodies were determined using indirect immunofluorescence in cells infected with the retrovirus. The mean titer was 1/234 in asymptomatic subjects and 1/2138 in symptomatic patients (p < 0.001). These results suggest an association between HTLV-I antibody titers and clinical stage of infected subjects.
本研究的目的是测定血清学阳性的有症状和无症状感染个体中的抗人嗜T淋巴细胞病毒I型（HTLV-I）抗体滴度。研究了107名感染个体（47名患有痉挛性截瘫，60名无症状）。使用间接免疫荧光法在感染逆转录病毒的细胞中测定HTLV-I抗体。无症状个体的平均滴度为1/234，有症状患者的平均滴度为1/2138（p<0.001）。这些结果表明HTLV-I抗体滴度与感染个体的临床分期之间存在关联。
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