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1988年和1993年麻疹暴发期间一所大学儿童医院的麻疹病例分析。

Analysis of measles cases in a university pediatric hospital during 1988 and 1993 outbreaks.

作者信息

Oğuz F, Sidal M, Uzel N, Ozgeneci A

机构信息

Department of Pediatrics, Istanbul University Faculty of Medicine, Capa.

出版信息

Turk J Pediatr. 1995 Apr-Jun;37(2):83-92.

PMID:7597773
Abstract

In Turkey, a mass measles immunization campaign was initiated in 1985, and the decision was made to administer the first of the measles vaccinations at nine months of age instead of 12-15 months. Following the campaign there was a decrease in the number of measles cases seen in the Outpatient Department of Istanbul University Children's Hospital in 1986 and 1987; however, after 1987 an increase was observed in measles cases, which continued until 1993. In order to investigate the current measles epidemics, we reevaluated the measles cases seen in our Outpatient Department from 1986 to 1993. We also investigated the vaccination status and the hospitalization and mortality rates of measles cases in the epidemics of 1988 and 1993. Since 1988 (except 1989) a significant increase (412-1375 percent) has been observed in measles cases, and between 1986 and 1993 more than half of all measles cases were in children older than four years of age. In 1988 and 1993 we found that most vaccinated measles cases were also in this age group, but the rate of complications and hospitalization among the vaccinated cases was lower compared to those who were not vaccinated.

摘要

在土耳其,1985年发起了一场大规模麻疹免疫运动,并决定在9个月大时而非12至15个月大时进行首次麻疹疫苗接种。运动之后,1986年和1987年伊斯坦布尔大学儿童医院门诊部所见麻疹病例数量有所下降;然而,1987年之后麻疹病例数量出现增加,并持续到1993年。为了调查当前的麻疹疫情,我们重新评估了1986年至1993年在我们门诊部所见的麻疹病例。我们还调查了1988年和1993年疫情中麻疹病例的疫苗接种状况、住院率和死亡率。自1988年(1989年除外)以来,麻疹病例显著增加(412%至1375%),1986年至1993年期间,所有麻疹病例的一半以上是4岁以上的儿童。1988年和1993年我们发现,大多数接种麻疹疫苗的病例也在这个年龄组,但与未接种疫苗的病例相比,接种疫苗病例的并发症和住院率较低。

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