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Internen Abteilung des a.ö. Krankenhauses der Kurstadt Baden.
Wien Med Wochenschr. 1995;145(5):112-7.
The drug therapy of osteoarthritis and mainly of the large joints consists in less severe cases in analgesic drugs. Nonsteroidal antirtheumatic drugs with their analgesic and antiinflammatory action are used in more severe cases. In elderly persons their side effects are more serious, therefore strict controls are important. Therapy with so-called chondroprotective substances is not yet established but the glycosaminoglycan-peptid and also the glucosaminosulfate may be able to slow down the arthrotic process. An additional therapeutic possibility are intraarticular injections of hyaluronic acid and the knee-lavage. A drug therapy in osteoarthritis should never be given as a single measure, but always in combination with physiotherapy and general measures like weight reduction or using a cane, etc.
骨关节炎（主要累及大关节）的药物治疗，在症状较轻的情况下使用镇痛药。在症状较严重的情况下，则使用具有镇痛和抗炎作用的非甾体类抗风湿药。在老年人中，这些药物的副作用更为严重，因此严格的监测很重要。所谓的软骨保护物质的治疗方法尚未确立，但糖胺聚糖肽以及氨基葡萄糖硫酸盐可能能够减缓关节病变进程。另一种治疗方法是关节内注射透明质酸和膝关节灌洗。骨关节炎的药物治疗绝不应作为单一措施使用，而应始终与物理治疗以及诸如减轻体重或使用拐杖等一般措施相结合。
