Wang H Y, Port J L, Hochwald S N, Burt M E
Thoracic Oncology Laboratory, Memorial Sloan-Kettering Cancer Center, New York, New York 10021, USA.
Ann Thorac Surg. 1995 Jul;60(1):211-2.
Isolated lung perfusion in the rat is a useful research tool. Pulmonary arteriotomy and venotomy repair is required for animal survival. Rat pulmonary vessels are fragile, thin, and small in caliber, making their repair the focal technical point. This technique has been improved. The arteriotomy now is closed with a single suture and the venotomy no longer requires repair. The lung is returned to its original anatomic position then compressed to stop bleeding. These improvements have improved animal morbidity and mortality markedly while reducing operating time.
大鼠离体肺灌注是一种有用的研究工具。为使动物存活，需要进行肺动脉切开术和静脉切开术修复。大鼠肺血管脆弱、壁薄且管径小，使其修复成为关键技术要点。该技术已得到改进。现在动脉切开术用单根缝线关闭，静脉切开术不再需要修复。将肺恢复到其原始解剖位置，然后压迫止血。这些改进显著降低了动物的发病率和死亡率，同时缩短了手术时间。
