Nagasaki Y, Kutsuna T, Iijima M, Kato M, Kataoka K, Kitano S, Kadoma Y
Department of Materials Science and Technology, Science University of Tokyo, Noda, Japan.
Bioconjug Chem. 1995 Mar-Apr;6(2):231-3. doi: 10.1021/bc00032a012.
Well-defined poly(ethylene oxide) (PEO) with a formyl group at one end and a hydroxyl group at the other terminus was synthesized by the anionic ring opening polymerization of ethylene oxide (EO) with a new organometallic initiator possessing an acetal moiety, potassium 3,3-diethoxypropyl alkoxide. Hydrolysis of the acetal moiety produced a formyl group-terminated heterobifunctional PEO with a hydroxyl group at the other end.
通过环氧乙烷（EO）与一种具有缩醛部分的新型有机金属引发剂3,3 - 二乙氧基丙醇钾进行阴离子开环聚合反应，合成了一种一端带有甲酰基、另一端带有羟基的结构明确的聚环氧乙烷（PEO）。缩醛部分的水解产生了一端为甲酰基、另一端为羟基的异双功能PEO。
