两种植物核酸酶对修饰核苷影响tRNA结构的研究
Influence of modified nucleosides on tRNA structure as probed by two plant nucleases.
作者信息
Przykorska A
机构信息
Institute of Biochemistry and Biophysics, PAN, Warshaw, Poland.
出版信息
Biochimie. 1995;77(1-2):109-12. doi: 10.1016/0300-9084(96)88113-2.
PMID:7599269
Abstract
Two new enzymatic probes have been used for structural investigations of native and unmodified transcript tRNA molecules. Both probes were single-strand-specific nucleases isolated from higher plants. The results obtained after enzymatic hydrolysis of tRNAs support the earlier hypothesis that posttranscriptional modifications in tRNA help to stabilize its structure and make it more rigid.
摘要
两种新的酶探针已被用于对天然未修饰的转录tRNA分子进行结构研究。这两种探针都是从高等植物中分离出来的单链特异性核酸酶。tRNA酶解后得到的结果支持了早期的假设，即tRNA的转录后修饰有助于稳定其结构并使其更具刚性。
Zotero 插件