Worck R H, Ibsen H, Andersen C B, Ibsen K K, Rasmussen F
Department of Clinical Physiology, University Hospital, Glostrup, Denmark.
Blood Press. 1995 Mar;4(2):113-6. doi: 10.3109/08037059509077579.
We report two cases of severe hypertension and unilateral renal dysplasia. No renal artery stenosis and no other urogenital malformations were found. In both cases we found substantially enhanced secretion of renin from the dysplastic kidney. After nephrectomy both patients obtained a distinctive and permanent reduction or normalization of blood pressure. In the two cases reported, regional renin release induced by ischemia is a very likely etiological factor.
我们报告了两例严重高血压合并单侧肾发育不良的病例。未发现肾动脉狭窄及其他泌尿生殖系统畸形。在这两例病例中，我们均发现发育不良的肾脏中肾素分泌显著增强。肾切除术后，两名患者的血压均出现明显且持久的降低或恢复正常。在所报告的这两例病例中，缺血诱导的局部肾素释放很可能是病因。
