Tauber T, Zimand S, Kotzer E
Pediatrics Dept., Assaf Harofeh Medical Center, Z'rifin.
Harefuah. 1995 May 15;128(10):611-2, 672.
The diagnosis of familial Mediterranean fever (FMF) is based on clinical evidence, since there is no specific diagnostic test. Manifestations are recurrent attacks of fever accompanied by serositis, mainly involving the peritoneum, pleura and joints. Although pericardial inflammation has been considered rare, when echocardiography is used to detect it, an incidence of 27% has been reported. We describe a boy of 11 and a girl of 15 years who developed recurrent pericarditis despite treatment with steroids, nonsteroidal anti-inflammatory drugs and pericardiocentesis. A few months after the first episode, both patients were admitted with typical bouts of FMF. Continuous prophylaxis with colchicine was initiated, and there were no further attacks during 18 and 10 month follow-ups, respectively. We conclude that acute or recurrent pericarditis in children or young adults of Mediterranean origin may be due to FMF.
家族性地中海热（FMF）的诊断基于临床证据，因为尚无特异性诊断测试。其表现为发热反复发作并伴有浆膜炎，主要累及腹膜、胸膜和关节。尽管心包炎一直被认为较为罕见，但当使用超声心动图检测时，报告的发病率为27%。我们描述了一名11岁男孩和一名15岁女孩，尽管接受了类固醇、非甾体抗炎药治疗及心包穿刺术，但仍反复发作心包炎。首次发作数月后，两名患者均因典型的FMF发作入院。开始使用秋水仙碱进行持续预防，在分别为期18个月和10个月的随访期间均未再发作。我们得出结论，地中海地区儿童或年轻人的急性或复发性心包炎可能是由FMF引起的。
