小鼠埃尔克癌基因定位于X染色体，而一种新的埃尔克癌基因（Elk3）定位于10号染色体。
Mouse Elk oncogene maps to chromosome X and a novel Elk oncogene (Elk3) maps to chromosome 10.
作者信息
Tamai Y, Taketo M, Nozaki M, Seldin M F
机构信息
Banyu Tsukuba Research Institute (Merck), Japan.
出版信息
Genomics. 1995 Mar 20;26(2):414-6. doi: 10.1016/0888-7543(95)80232-b.
The Elk protein is a member of the Ets family found in both vertebrates and invertebrates. Human ELK1 encoded by ELK1 binds alone or together with serum response factor to DNA and regulates gene expression in a variety of biological processes. Using a panel of interspecific backcross mice, we have mapped the Elk oncogene (Elk) and a novel type Elk oncogene (Elk3), closely related to ELK1. Elk maps to Chr X, and Elk3 maps to the proximal region of Chr 10.
Elk蛋白是一种在脊椎动物和无脊椎动物中均有发现的Ets家族成员。由ELK1编码的人类ELK1可单独或与血清反应因子一起结合到DNA上，并在多种生物学过程中调节基因表达。利用一组种间回交小鼠，我们已定位了与ELK1密切相关的Elk癌基因（Elk）和一种新型Elk癌基因（Elk3）。Elk定位于X染色体，Elk3定位于10号染色体的近端区域。
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