适于胎龄新生儿的机体水分分布

Body water distribution in newborn infants appropriate for gestational age.

作者信息

Singhi S C, Ganguli N K, Bhakoo O N, Dhall K, Sood V, Kaur A

机构信息

Department of Paediatrics, Postgraduate Institute of Medical Education & Research, Chandigarh.

出版信息

Indian J Med Res. 1995 May;101:193-200.

PMID:7601497

Abstract

Total body water (TBW), extracellular water (ECW) and intracellular water (ICW) were measured within 6 h of birth in 99 appropriate for gestational age (AGA) infants. The two groups of infants included were term (mean +/- SD gestation 272 +/- 7 days) and preterm (mean +/- SD gestation 238 +/- 11 days) infants. The mean TBW +/- SD was 777 +/- 26 ml/kg in preterm infants and 737 +/- 26 ml/kg in term infants. The corresponding ECW was 349 +/- 26 ml/kg and 331 +/- 30 ml/kg respectively. Weight was the best correlate of TBW (r = 0.98) and ECW (r = 0.92) volumes. TBW per unit of body weight showed significant decline with increasing gestation (r = -0.54) and birth weight (r = -0.51). ICW per kg showed a moderate correlation with TBW (r = 0.63), whereas ECW per kg had a low correlation (r = 0.35) with it. TBW/kg in our infants was comparable to infants from other ethnic groups. ICW/kg, however, was consistently higher and ECW/kg lower at all stages of maturation in Indian infants as compared to Caucacian and Negroid infants.

摘要

对99名适于胎龄（AGA）婴儿在出生后6小时内测量了全身水（TBW）、细胞外液（ECW）和细胞内液（ICW）。纳入的两组婴儿分别为足月儿（平均±标准差妊娠272±7天）和早产儿（平均±标准差妊娠238±11天）。早产儿的平均TBW±标准差为777±26 ml/kg，足月儿为737±26 ml/kg。相应的ECW分别为349±26 ml/kg和331±30 ml/kg。体重是TBW（r = 0.98）和ECW（r = 0.92）容量的最佳相关因素。每单位体重的TBW随着胎龄增加（r = -0.54）和出生体重增加（r = -0.51）而显著下降。每千克ICW与TBW呈中度相关（r = 0.63），而每千克ECW与之相关性较低（r = 0.35）。我们研究中婴儿的TBW/kg与其他种族的婴儿相当。然而，与白种人和黑人婴儿相比，印度婴儿在所有成熟阶段的ICW/kg始终较高，ECW/kg较低。