Bruce A, Andersson M, Arvidsson B, Isaksson B
Scand J Clin Lab Invest. 1980 Sep;40(5):461-73. doi: 10.3109/00365518009101869.
In 134 males and 242 females, aged 20-70 years, most of them randomly selected from population studies, the body composition was estimated from the measurements of body height (BH), body weight (BW), total body potassium (TBK) and total body water (TBW). TBK was measured with isotope dilution technique using 42K or determined as 40K in a whole body counter. TBW was determined with an isotope dilution technique using tritiated water, assayed in urine or plasma. From these data, body cell mass (BCM), intra- and extra-cellular water (ICW and ECW, resp.) and body fat (BF) were calculated for each individual. Significant correlations were found between age versus TBK, ECW, BF and ECW/ICW; between BW versus TBK, TBW, ECW, BF and ECW/ICW; (females only) and between BH versus TBK, TBW, ECW (females only) and ECW/ICW. For the prediction of TBK, TBW and BF, multiple regression equations based on BW, BH and age are given. These equations are also presented diagrammatically. The problems with the methods used are considered as well as the applicability of the formulas for the calculation of BCM etc. The predictive value of the results when both TBW and TBK are used for the calculation of body composition data is discussed and compared with similar results, based on TBW or TBK only. It is concluded, that the most reliable method for calculation of BF is to estimate both TBW and TBK.
在134名男性和242名女性中,年龄在20至70岁之间,他们大多是从人群研究中随机选取的,通过测量身高(BH)、体重(BW)、总体钾(TBK)和总体水(TBW)来估算身体成分。TBK采用同位素稀释技术,使用42K进行测量,或在全身计数器中测定为40K。TBW采用同位素稀释技术,使用氚水进行测定,在尿液或血浆中进行分析。根据这些数据,为每个个体计算身体细胞质量(BCM)、细胞内和细胞外水(分别为ICW和ECW)以及身体脂肪(BF)。发现年龄与TBK、ECW、BF和ECW/ICW之间存在显著相关性;体重与TBK、TBW、ECW、BF和ECW/ICW之间存在显著相关性(仅女性);身高与TBK、TBW、ECW(仅女性)和ECW/ICW之间存在显著相关性。给出了基于体重、身高和年龄预测TBK、TBW和BF的多元回归方程。这些方程也以图表形式呈现。考虑了所用方法存在的问题以及计算BCM等公式的适用性。讨论了同时使用TBW和TBK计算身体成分数据时结果的预测价值,并与仅基于TBW或TBK的类似结果进行了比较。得出的结论是,计算BF最可靠的方法是同时估算TBW和TBK。