强直性脊柱炎的谱系

The spectrum of ankylosing spondylitis.

作者信息

Harley J B, Scofield R H

机构信息

Endocrinology and Metabolism Section, University of Oklahoma Health Sciences Center, USA.

出版信息

Hosp Pract (1995). 1995 Jul 15;30(7):37-43, 46. doi: 10.1080/21548331.1995.11443227.

DOI:10.1080/21548331.1995.11443227

PMID:7601896

Abstract

Sacroiliac involvement is an early hallmark, but even so, patients with ankylosing spondylitis present a remarkable spectrum of disease. Research probing associations among spondylitis, enteric bacterial infection, and host expression of HLA-B27 may offer etiologic clues and point the way to disease-specific therapies.

摘要

骶髂关节受累是早期特征，但即便如此，强直性脊柱炎患者的疾病表现仍具有显著的多样性。探究脊柱炎、肠道细菌感染与HLA - B27宿主表达之间关联的研究可能会提供病因线索，并为疾病特异性治疗指明方向。