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强直性脊柱炎

Ankylosing spondylitis.

作者信息

Wolf Jeanette, Fasching Peter

机构信息

5th Department of Internal Medicine (Endocrinology and Rheumatology), Wilhelminen-Hospital, Vienna, Austria.

出版信息

Wien Med Wochenschr. 2010 May;160(9-10):211-4. doi: 10.1007/s10354-010-0793-2.

DOI:10.1007/s10354-010-0793-2
PMID:20632147
Abstract

Ankylosing Spondylitis (AS) is an autoimmune disease of unknown cause belonging to the group of spondyloarthritides associated with HLA B27. This disease affects the spine and sacroiliac joints, but may also concern peripheral joints and different organs. Symptoms include morning stiffness and dull low back pain, both improving by exercise. AS causes reduction in life expectancy due to subsequent manifestation in different organs, so early diagnosis and treatment are of great importance.

摘要

强直性脊柱炎（AS）是一种病因不明的自身免疫性疾病，属于与HLA B27相关的脊柱关节炎组。这种疾病会影响脊柱和骶髂关节，但也可能累及外周关节和不同器官。症状包括晨僵和钝性下背痛，运动后均可缓解。由于随后会在不同器官出现病变，AS会导致预期寿命缩短，因此早期诊断和治疗非常重要。

相似文献

1
Ankylosing spondylitis.强直性脊柱炎
Wien Med Wochenschr. 2010 May;160(9-10):211-4. doi: 10.1007/s10354-010-0793-2.
2
[Spondyloarthritides].[脊柱关节炎]
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3
Early diagnosis crucial in ankylosing spondylitis.早期诊断对强直性脊柱炎至关重要。
Practitioner. 2011 Dec;255(1746):21-4, 2.
4
Ankylosing spondylitis and related spondyloarthropathies: the dramatic advances in the past decade.强直性脊柱炎及相关脊柱关节病：过去十年的重大进展
Rheumatology (Oxford). 2011 Apr;50(4):637-9. doi: 10.1093/rheumatology/keq433.
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Ankylosing spondylitis: a contemporary perspective on diagnosis and treatment.强直性脊柱炎：诊断与治疗的当代观点
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[Spondyloarthritides].[脊柱关节炎]
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7
The occurrence of sacroiliitis in HLA-B*35-positive patients with undifferentiated spondyloarthritis. A cross sectional MRI study.HLA-B*35 阳性的未分化脊柱关节炎患者中出现的骶髂关节炎。一项横断面 MRI 研究。
Clin Rheumatol. 2020 Aug;39(8):2299-2306. doi: 10.1007/s10067-020-04999-4. Epub 2020 Feb 27.
8
Severity of baseline magnetic resonance imaging-evident sacroiliitis and HLA-B27 status in early inflammatory back pain predict radiographically evident ankylosing spondylitis at eight years.早期炎性背痛患者基线磁共振成像显示的骶髂关节炎严重程度及HLA - B27状态可预测八年后放射学可见的强直性脊柱炎。
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[Spondyloarthritides].[脊柱关节炎]
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Ankylosing spondylitis and bamboo spine.强直性脊柱炎与竹节样脊柱。
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Bioinformatics Analysis of the Molecular Mechanism and Potential Treatment Target of Ankylosing Spondylitis.生物信息学分析强直性脊柱炎的分子机制及潜在治疗靶点。
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The effects of β-D-mannuronic acid (M2000), as a novel NSAID, on COX1 and COX2 activities and gene expression in ankylosing spondylitis patients and the murine monocyte/macrophage, J774 cell line.

本文引用的文献

1
Preliminary core sets for endpoints in ankylosing spondylitis. Assessments in Ankylosing Spondylitis Working Group.强直性脊柱炎终点指标初步核心集。强直性脊柱炎工作组评估。
J Rheumatol. 1997 Nov;24(11):2225-9.
2
A new approach to defining disease status in ankylosing spondylitis: the Bath Ankylosing Spondylitis Disease Activity Index.一种定义强直性脊柱炎疾病状态的新方法：巴斯强直性脊柱炎疾病活动指数。
J Rheumatol. 1994 Dec;21(12):2286-91.
3
A new approach to defining functional ability in ankylosing spondylitis: the development of the Bath Ankylosing Spondylitis Functional Index.
β-D-甘露糖醛酸（M2000）作为一种新型 NSAID，对强直性脊柱炎患者和小鼠单核细胞/巨噬细胞 J774 细胞系中 COX1 和 COX2 活性和基因表达的影响。
Inflammopharmacology. 2018 Apr;26(2):375-384. doi: 10.1007/s10787-017-0386-4. Epub 2017 Aug 17.
4
Increased occurrence of spinal fractures related to ankylosing spondylitis: a prospective 22-year cohort study in 17,764 patients from a national registry in Sweden.与强直性脊柱炎相关的脊柱骨折发生率增加：一项对瑞典国家登记处17764名患者进行的为期22年的前瞻性队列研究。
Patient Saf Surg. 2013 Jan 7;7(1):2. doi: 10.1186/1754-9493-7-2.
5
[Seronegative spondylarthritis].[血清阴性脊柱关节炎]
Wien Med Wochenschr. 2010 May;160(9-10):209-10. doi: 10.1007/s10354-010-0792-3.
一种定义强直性脊柱炎功能能力的新方法：巴氏强直性脊柱炎功能指数的制定。
J Rheumatol. 1994 Dec;21(12):2281-5.
4
Evaluation of diagnostic criteria for ankylosing spondylitis. A proposal for modification of the New York criteria.强直性脊柱炎诊断标准的评估。对纽约标准进行修订的提议。
Arthritis Rheum. 1984 Apr;27(4):361-8. doi: 10.1002/art.1780270401.
5
Associations between ankylosing spondylitis, psoriatic arthritis, Reiter's disease, the intestinal arthropathies, and Behcet's syndrome.强直性脊柱炎、银屑病关节炎、赖特综合征、肠道关节病和白塞综合征之间的关联。
Medicine (Baltimore). 1974 Sep;53(5):343-64. doi: 10.1097/00005792-197409000-00002.