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新生儿红斑狼疮中的皮肤毛细血管扩张

Cutaneous telangiectases in neonatal lupus erythematosus.

作者信息

Thornton C M, Eichenfield L F, Shinall E A, Siegfried E, Rabinowitz L G, Esterly N B, Lucky A W, Friedlander S F

机构信息

Division of Dermatology, University of California, San Diego, USA.

出版信息

J Am Acad Dermatol. 1995 Jul;33(1):19-25. doi: 10.1016/0190-9622(95)90004-7.

Abstract

BACKGROUND

Persistent telangiectases are a feature of neonatal lupus erythematosus (NLE) but have generally been noted in areas of prior inflammatory disease. The occurrence of vascular macules and papules at sites without preceding dermatitis has not been reported in NLE.

OBJECTIVE

Our purpose was to emphasize a previously unidentified aspect of cutaneous NLE: the presence of angiomatous or matlike telangiectases in sites without antecedent or concurrent dermatitis.

METHODS

We describe seven patients in which telangiectatic macules or angiomatous papules were primary or early features of NLE.

RESULTS

Five infants lacked a history of preceding or concurrent inflammatory lesions at sites of telangiectasia development. In four infants findings included vulvar or inguinal angiomatous papules.

CONCLUSION

Telangiectases may be a presenting feature of NLE, can be found in sun-protected sites, and may occur independent of "lupus dermatitis."

摘要

背景

持久性毛细血管扩张是新生儿红斑狼疮(NLE)的一个特征,但通常见于先前有炎症性疾病的部位。NLE中尚未见在无先前皮炎的部位出现血管性斑疹和丘疹的报道。

目的

我们的目的是强调皮肤型NLE一个先前未被认识到的方面:在无先前或同时存在的皮炎部位出现血管瘤样或席状毛细血管扩张。

方法

我们描述了7例以毛细血管扩张性斑疹或血管瘤样丘疹为NLE主要或早期特征的患者。

结果

5例婴儿在毛细血管扩张发生部位无先前或同时存在炎症性损害的病史。4例婴儿的表现为外阴或腹股沟血管瘤样丘疹。

结论

毛细血管扩张可能是NLE的一个表现特征,可出现在防晒部位,且可能独立于“狼疮性皮炎”而发生。

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