Maroof M, Khan R M, Bhatti T H
Department of Anaesthesiology, King Fahad National Guard Hospital, Riyadh, Saudi Arabia.
J Pak Med Assoc. 1995 Feb;45(2):43-4.
Ten adult patients undergoing one lung ventilation for elective thoracotomy were selected. All these patients failed to maintain oxygen saturation (SaO2) > 90% despite administration of 100% oxygen to the non-ventilated lung (NVL). These patients were studied for the efficacy of continuous positive airway pressure (CPAP) of the NVL using air and oxygen combination (FiO20.5) employing a variable FiO2CPAP system. It was observed that application of CPAP (5-10 cm H2O) with a mixture of air and oxygen to the NVL increased the SaO2 > 90% in all these patients. This could be attributed to nitrogen in air which prevented absorption atelectasis in the NVL. This produced a better ventilation/perfusion ratio and hence the increased oxygen saturation.
选取了10例接受择期开胸手术单肺通气的成年患者。尽管对非通气肺（NVL）给予100%氧气，所有这些患者仍无法维持氧饱和度（SaO2）>90%。使用可变氧浓度持续气道正压通气（CPAP）系统，研究了这些患者对非通气肺采用空气和氧气混合（FiO2 0.5）进行持续气道正压通气（CPAP）的效果。观察到对非通气肺应用5-10 cm H2O的空气和氧气混合的CPAP可使所有这些患者的SaO2>90%。这可能归因于空气中的氮气可防止非通气肺出现吸收性肺不张。这产生了更好的通气/灌注比，从而提高了氧饱和度。
