Hosoda S, Kimata S, Tamura K, Nakamura M, Toshima H, Shibata J, Minamino R, Takano T, Hiramori K, Yaginuma T
Tokyo Women's Medical College, Heart Institute of Japan.
Jpn Circ J. 1995 Mar;59(3):130-6. doi: 10.1253/jcj.59.130.
The subjects consisted of 2,733 patients with acute myocardial infarction (AMI) who were admitted to our 11 institutions between 1983 and 1988, examined by coronary arteriography, and discharged alive. The patients were followed for an average of 2.9 years after discharge. During the follow-up period, re-infarction occurred in 172 patients (6.3%). The factors associated with re-infarction were total cholesterol of more than 250 mg/dl, HDL-cholesterol of less than 35 mg/dl and diabetes mellitus. The rate of re-infarction was also high in patients who had had a previous infarction before admission, angina pectoris before or after the onset of AMI or multiple-vessel disease. In contrast, intracoronary thrombolysis reduced the rate of re-infarction.
研究对象包括1983年至1988年间入住我们11家机构的2733例急性心肌梗死（AMI）患者，这些患者均接受了冠状动脉造影检查并存活出院。患者出院后平均随访2.9年。随访期间，172例患者（6.3%）发生再梗死。与再梗死相关的因素包括总胆固醇超过250mg/dl、高密度脂蛋白胆固醇低于35mg/dl以及糖尿病。入院前曾有过梗死、AMI发作前后有心绞痛或多支血管病变的患者再梗死率也较高。相比之下，冠状动脉内溶栓降低了再梗死率。
