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WF/PmWp-"fz"(模糊)大鼠的解剖学和生理学特征

Anatomic and physiologic characterization of the WF/PmWp-"fz" (fuzzy) rat.

作者信息

Marit G B, Young S M, Hadick C L

机构信息

Toxicology Division, Armstrong Laboratory, Wright-Patterson AFB, OH 45433-7400, USA.

出版信息

Lab Anim Sci. 1995 Apr;45(2):184-90.

PMID:7603022
Abstract

The WF/PmWp-"fz" rat is an inbred strain of hypotrichotic rat derived from a Wistar Furth colony. This strain, also known as the "fuzzy rat," has been used for dermal toxicity research; however, little is known about its longevity and age-related physiologic and pathologic changes. Presented are basic anatomic and physiologic parameters, collected for each sex at five ages, including hematologic and clinical biochemical profiles, organ and body weights, and a characterization of gross and histopathologic findings.

摘要

WF/PmWp-"fz"大鼠是一种源自Wistar Furth群体的无毛近交系大鼠。该品系,也被称为“模糊鼠”,已用于皮肤毒性研究;然而,对其寿命以及与年龄相关的生理和病理变化知之甚少。本文展示了在五个年龄段为每种性别收集的基本解剖学和生理学参数,包括血液学和临床生化指标、器官和体重,以及大体和组织病理学发现的特征。

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