Stein M E, Drumea K, Ben-Itshak O, Hoffman A, Eyal A, Moshkovitz B, Haim N
Chemotherapy Unit, Northern Israel Oncology Center, Haifa.
Med Pediatr Oncol. 1995 Aug;25(2):126-9. doi: 10.1002/mpo.2950250216.
Arterial tumor embolization is a rare but serious complication of neoplastic disease. The majority of these tumors are associated with primary or secondary lung malignancies, originating from pulmonary vein metastasis or from an atrial mass. Malignant germ cell tumors primarily disseminate to the retroperitoneal lymph nodes and lung, and to the brain and liver later in the course of the disease. A germ cell tumor metastasis embolizing to the iliac-femoral arterial system has not yet been reported. We report a metastatic embolism in a patient with disseminated embryonal cell carcinoma causing acute limb ischemia, managed by surgical embolectomy. The sudden development of limb ischemia in a patient with a germ cell tumor should alert the physician to the possibility of tumor embolism.
动脉肿瘤栓塞是肿瘤疾病中一种罕见但严重的并发症。这些肿瘤大多与原发性或继发性肺恶性肿瘤相关，起源于肺静脉转移或心房肿块。恶性生殖细胞肿瘤主要扩散至腹膜后淋巴结和肺部，在疾病后期还会扩散至脑和肝脏。尚未有生殖细胞肿瘤转移栓塞至髂股动脉系统的报道。我们报告了一例播散性胚胎细胞癌患者发生的转移性栓塞，导致急性肢体缺血，通过手术取栓进行治疗。生殖细胞肿瘤患者突然出现肢体缺血应提醒医生注意肿瘤栓塞的可能性。
