Menard R M, Delaire J, Schendel S A
Division of Plastic and Reconstructive Surgery, Stanford University School of Medicine, Calif, USA.
Plast Reconstr Surg. 1995 Jul;96(1):27-33. doi: 10.1097/00006534-199507000-00004.
Variable degrees of macroglossia have been noted in patients with Beckwith-Wiedemann syndrome. Past studies have shown that a major effect of the macroglossia is protrusion of dentoalveolar structures, resulting in an anterior open bite and a prognathic mandibular appearance secondary to an abnormally obtuse gonial angle and increased effective mandibular length. In our series of 11 Beckwith-Wiedemann syndrome patients we have observed that early correction of the macroglossia by means of partial glossectomy has resulted in decreased anterior open bite and mandibular prognathism as compared with patients managed conservatively.
在贝克威思-维德曼综合征患者中已观察到不同程度的巨舌症。过去的研究表明，巨舌症的一个主要影响是牙槽结构突出，导致前牙开颌，以及由于下颌角异常钝角和有效下颌长度增加而继发的下颌前突外观。在我们的11例贝克威思-维德曼综合征患者系列中，我们观察到，与保守治疗的患者相比，通过部分舌切除术早期矫正巨舌症可减少前牙开颌和下颌前突。
