Acsády G Y, Nemes A, Sótonyi P
Department of Cardiac and Vascular Surgery, Semmelweis University Medical School, Budapest, Hungary.
Acta Chir Hung. 1994;34(1-2):115-32.
In altogether 48 adult mongrel dogs of both sexes with body weights between 15 and 25 kg, 3-5 cm long portions of the subrenal inferior vena cava were replaced by different vascular prostheses under intratracheal anaesthesia. During surgery, heparin sodium in an amount of 0.1 ml/kg body weight was administered intravenously to the animals, which was bound at the end of the surgery. In the postoperative period neither anticoagulant therapy measures for the inhibition of platelet aggregation were applied. In half of the experiments a 6-8 mm long arteriovenous fistula was prepared between the femoral artery and the femoral vein which was maintained permanently. The vascular prostheses were either of biological or of synthetic type; in one group within each type, prostheses without external support were implanted, while in the other group the prostheses had an external support.
在总共48只体重在15至25千克之间的成年杂种犬（雌雄皆有）中，在气管内麻醉下，用不同的血管假体替换肾下下腔静脉3 - 5厘米长的部分。手术期间，以0.1毫升/千克体重的剂量向动物静脉注射肝素钠，在手术结束时将其中和。术后期间未采取抑制血小板聚集的抗凝治疗措施。在一半的实验中，在股动脉和股静脉之间制备了一个6 - 8毫米长的永久性动静脉瘘。血管假体分为生物型或合成型；在每种类型中的一组，植入无外部支撑的假体，而在另一组中，假体有外部支撑。
