Szendrói M, Vizkelety T, Antal I, van Loon K
Department of Orthopaedics, Semmelweis University Medical School, Budapest, Hungary.
Acta Chir Hung. 1994;34(1-2):17-28.
A retrospective clinical review of 28 low- and 47 high-grade bone tumours, managed by limb salvage operations, was performed in the Orthopaedics Department of the Semmelweis University Medical School, Budapest. The mean follow-up period was 37.2 months. Ten bone tumours were classified as stage I/A, 18 as I/B, 16 as II/A and 31 as II/B. The overall 3 years survival rate was 97% in low-grade bone tumours, 84% in osteosarcomas and 50% in Ewing's sarcomas. Local recurrences were observed in 14%. Tumour prostheses were implanted in 25 patients (33%); 2 complications in this material were seen. In 50 patients resection and reconstruction with autografts or allografts were performed; 13 complications (26%) were registered in 9 patients. These results suggest that limb saving surgery is an acceptable method in selected cases of early recognized bone tumours which respond well to the chemotherapy.
在布达佩斯塞梅尔维斯大学医学院骨科,对28例低度和47例高度骨肿瘤患者进行了保肢手术的回顾性临床研究。平均随访期为37.2个月。10例骨肿瘤被分类为I/A期,18例为I/B期,16例为II/A期,31例为II/B期。低度骨肿瘤的3年总生存率为97%,骨肉瘤为84%,尤因肉瘤为50%。局部复发率为14%。25例患者(33%)植入了肿瘤假体;该材料出现了2例并发症。50例患者采用自体移植或同种异体移植进行了切除和重建;9例患者出现了13例并发症(26%)。这些结果表明,保肢手术在部分早期确诊且对化疗反应良好的骨肿瘤病例中是一种可接受的方法。