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梗阻性无精子症的诊断与治疗

Diagnosis and treatment of obstructive azoospermia.

作者信息

Lenk S, Oesterwitz H

机构信息

Klinik und Poliklinik für Urologie, Universitätsklinikum Charité der Humboldt-Universität zu Berlin, Germany.

出版信息

Acta Chir Hung. 1994;34(1-2):183-8.

PMID:7604622
Abstract

Obstructive azoospermia is an important reason for male infertility. The obstruction can be caused by congenital, postinflammatory or iatrogenic factors (herniotomy, orchidopexy, vasectomy). Diagnosis includes anamnesis, physical examination, determination of hormone levels (FSH, LH, testosterone), semen analysis and biopsy from both tests. 37 patients with suspected obstructive azoospermia and 19 patients after previous vasectomy underwent scrotal exploration. Following an intraoperative semen analysis, vasoepididymostomy was performed in 12 patients, vasovasostomy in 19 patients. After vasoepididymostomy, patency was stated in 42%, and pregnancy followed in 17%. The patency after vasectomy reversal was 85%. The success of treatment of obstructive azoospermia depends on the duration of obstruction, on the location and on the microsurgical technique applied.

摘要

梗阻性无精子症是男性不育的一个重要原因。梗阻可由先天性、炎症后或医源性因素(疝修补术、睾丸固定术、输精管切除术)引起。诊断包括问诊、体格检查、激素水平测定(促卵泡生成素、促黄体生成素、睾酮)、精液分析以及双侧睾丸活检。37例疑似梗阻性无精子症患者和19例既往接受输精管切除术的患者接受了阴囊探查。术中进行精液分析后,12例患者行附睾输精管吻合术,19例患者行输精管吻合术。附睾输精管吻合术后,42%的患者实现了通畅,17%的患者随后怀孕。输精管复通术后的通畅率为85%。梗阻性无精子症的治疗成功与否取决于梗阻的持续时间、梗阻部位以及所应用的显微外科技术。

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