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局部丝裂霉素C疗法用于预防经激光治疗的浅表性膀胱肿瘤复发

Local mitomycin-C therapy in relapse-prevention of superficial bladder neoplasms treated by means of laser.

作者信息

Szemes Z, Kovács R

机构信息

Urological Ward, Central Hospital, Budapest, Hungary.

出版信息

Acta Chir Hung. 1994;34(1-2):5-10.

PMID:7604628
Abstract

Authors report on local mitomycin-C (MTM-C) therapy applied subsequent to the treatment by means of Nd-YAG laser in 59 superficial (Ta-T1) bladder neoplasms. Relapse-rate in the neoplasms could be reduced by using MTM-C accompanied by minor side-effects. Seventy-two % of patients have been free from relapse for the mean 44-month follow-up period. Authors also suggest that laser therapy may favourably be completed by local chemoprophylaxis in "high-risk" type superficial bladder neoplasms.

摘要

作者报告了在59例浅表性(Ta-T1期)膀胱肿瘤患者中,在钕钇铝石榴石激光治疗后应用局部丝裂霉素C(MTM-C)治疗的情况。使用MTM-C可降低肿瘤的复发率,且副作用较小。在平均44个月的随访期内,72%的患者无复发。作者还建议,在“高危”型浅表性膀胱肿瘤中,激光治疗可通过局部化学预防得到更好的效果。

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