Kanerva L, Mäkinen-Kiljunen S, Kiistala R, Granlund H
Institute of Occupational Health, Helsinki, Finland.
Allergy. 1995 Feb;50(2):174-8. doi: 10.1111/j.1398-9995.1995.tb05076.x.
Occupational allergy caused by plants is seldom reported although it is probably relatively common. We report on a 22-year-old male atopic caretaker of plants who developed IgE-mediated allergic rhinitis, laryngitis, pharyngitis, and contact and generalized urticaria caused by exposure to spathe flower (Spathiphyllum wallisii) while he was working for a firm that supplied plants to offices. He also had an asthmatic attack at work, but in bronchial provocation tests conducted 8 months after he had stopped doing the work in question, he developed rhinoconjunctivitis, pharyngitis, and laryngitis, but exhibited neither bronchial reaction nor fall in PEF values. Prick tests with spathe flower gave 3+ reactions for exudates from the flower, pollen, stem, and leaves. He also had several positive reactions to fruits, vegetables, and spices, but not to natural rubber latex. The radioallergosorbent test with spathe flower was positive (3.4 PRU/ml, close to class 3). In protein staining with SDS-PAGE, one heavy band was detected at about 14 kDa, and other faint bands were visible on both sides. Six faint bands were detected at the mol. mass range of 30-67 kDa. In IgE immunoblotting, one heavy band was detected at about 14 kDa. The patient became symptomless after he had ceased working with plants.
植物引起的职业性过敏虽可能相对常见，但报道较少。我们报告一例22岁的男性植物过敏性护理员，他在一家为办公室供应植物的公司工作时，因接触白鹤芋（Spathiphyllum wallisii）而出现IgE介导的过敏性鼻炎、喉炎、咽炎、接触性和全身性荨麻疹。他在工作时还发生了哮喘发作，但在停止从事相关工作8个月后进行的支气管激发试验中，他出现了鼻结膜炎、咽炎和喉炎，但未出现支气管反应，呼气峰值流速（PEF）值也未下降。用白鹤芋进行点刺试验时，花的渗出液、花粉、茎和叶均出现3+反应。他对水果、蔬菜和香料也有几种阳性反应，但对天然橡胶乳胶无反应。用白鹤芋进行的放射变应原吸附试验呈阳性（3.4 PRU/ml，接近3级）。在SDS-PAGE蛋白质染色中，在约14 kDa处检测到一条重带，两侧可见其他淡带。在30 - 67 kDa的分子量范围内检测到六条淡带。在IgE免疫印迹中，在约14 kDa处检测到一条重带。患者停止接触植物后症状消失。
