Maeda N, Watanabe K, Negoro T, Aso K, Haga Y, Kito M, Ohki T, Ito K, Kato T
Department of Pediatrics, Nagoya University School of Medicine, Japan.
Pediatr Neurol. 1993 Nov-Dec;9(6):430-4. doi: 10.1016/0887-8994(93)90021-4.
Positron emission tomography (PET) using 18F-labeled 2-deoxy-D-glucose was performed serially in 5 infants with idiopathic West syndrome. While tonic spasms persisted, 2 infants had hypometabolism in the bilateral temporo-parieto-occipital regions, which disappeared after cessation of spasms. In 2 other infants, PET revealed focal hypometabolism in the temporal region a few months after the disappearance of tonic spasms, but subsequent PET studies were normal. PET can detect transient metabolic abnormalities of the cerebral cortex which may be associated with the pathophysiology of West syndrome.
对5例特发性韦斯特综合征婴儿连续进行了使用18F标记的2-脱氧-D-葡萄糖的正电子发射断层扫描（PET）。在强直痉挛持续期间，2例婴儿双侧颞顶枕区代谢减低，痉挛停止后消失。另外2例婴儿在强直痉挛消失数月后PET显示颞区局灶性代谢减低，但随后的PET检查正常。PET可检测到可能与韦斯特综合征病理生理学相关的大脑皮质短暂性代谢异常。
