Shuangshoti S, Vajragupta L
Department of Pathology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Clin Neuropathol. 1995 Mar-Apr;14(2):82-5.
A 25-year-old man had angiolipoma of the left thalamus producing sudden severe headache, coma, right hemiparalysis, and aphasia as usually observed in cerebrovascular disease. The patient remained right hemiparalytic and aphasic after removal of the thalamic lesion. A vascular lesion was also detected angiographically in the left lateral ventricular choroid plexus but was not excised. Only 3 intracranial angiolipomas including the current instance were on record. However, it was only in our patient that the lesion suddenly presented with intracerebral hemorrhage. The pathogenesis of the angiolipoma was suggested to be associated with maldifferentiation of mesenchyme and/or its derivatives toward the vascular and adipose tissue within the same mass, resulting in the formation of the angiolipoma.
一名25岁男性患有左丘脑血管脂肪瘤，出现了通常在脑血管疾病中观察到的突发严重头痛、昏迷、右侧偏瘫和失语。切除丘脑病变后，患者仍遗留右侧偏瘫和失语。血管造影还在左侧侧脑室脉络丛检测到一个血管病变，但未予切除。包括本例在内，仅有3例颅内血管脂肪瘤有记录。然而，只有我们的患者病变突然出现脑内出血。血管脂肪瘤的发病机制被认为与间充质和/或其衍生物在同一肿块内朝着血管和脂肪组织的分化异常有关，从而导致血管脂肪瘤的形成。
